API's and Intermediaries

Available

(4-(Pyridin-2-ylcarbamoyl)phenyl)boronic Acid

Acalabrutinib Intermediate — boronic acid coupling partner

CAS No.: 850568-25-1
M. Formula: C12H11BN2O3
MW: 242.04

Available

Benzyl (S)-2-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate

Acalabrutinib KSM — pyrrolidine-imidazopyrazine core

CAS No.: 1420478-88-1
M. Formula: C18H18BrN5O2
MW: 416.28

Available

N-(Benzyloxycarbonyl)-L-proline

Acalabrutinib KSM — Cbz-protected L-proline

CAS No.: 1148-11-4
M. Formula: C13H15NO4
MW: 249.26

Available

N-[(2S)-2-[[(Methylsulfonyl)oxy]methyl]-1-oxo-3-phenylpropyl]-glycine ethyl ester

Alvimopan Dihydrate Intermediate

CAS No.: 1314751-85-3
M. Formula: C15H21NO6S
MW: 343.39

Available

N-Methoxycarbonyl-L-tert-leucine

Atazanavir Sulfate KSM

CAS No.: 162537-11-3
M. Formula: C8H15NO4
MW: 189.21

Available

(S)-1-Benzylpyrrolidin-3-ol

Barnidipine HCl Chiral KSM

CAS No.: 101385-90-4
M. Formula: C11H15NO
MW: 177.25

Available

2-(2-(4-(2-(4-(1-(2-Ethoxyethyl)-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)ethyl)phenyl)propan-2-yl)-4,4-dimethyl-4,5-dihydrooxazole

Bilastine Penultimate Intermediate

CAS No.: 202189-77-3
M. Formula: C32H44N4O2
MW: 516.73

Available

tert-Butyl 4-(1H-benzo[d]imidazol-2-yl)piperidine-1-carboxylate

Bilastine Intermediate — Boc-protected benzimidazole piperidine

CAS No.: 953071-73-3
M. Formula: C17H23N3O2
MW: 301.39

Available

4-tert-Butyl-N-(6-chloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide

Bosentan Hydrate Penultimate Intermediate

CAS No.: 150727-06-3
M. Formula: C25H24ClN5O4S
MW: 526.01

Available

5-(2-Methoxyphenoxy)-[2,2'-bipyrimidine]-4,6(1H,5H)-dione

Bosentan Hydrate Intermediate

CAS No.: 150728-12-4
M. Formula: C15H12N4O4
MW: 312.29

Available

7-Hydroxyquinolin-2(1H)-one

Brexpiprazole KSM — 7-hydroxycarbostyril

CAS No.: 70500-72-0
M. Formula: C9H7NO2
MW: 161.16

Available

8-(Benzo[b]thiophen-4-yl)-5,8-diazaspiro[4.5]decan-5-ium Bromide

Brexpiprazole Diazaspirodecane Intermediate

CAS No.: 2143944-65-2
M. Formula: C16H21BrN2S
MW: 353.32

Available

(2R,3S,5R)-5-(5-((E)-2-Bromovinyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-(((4-chlorobenzoyl)oxy)methyl)tetrahydrofuran-3-yl 4-chlorobenzoate

Brivudine Protected Nucleoside Intermediate

CAS No.: 87531-10-0
M. Formula: C25H19BrCl2N2O7
MW: 610.24

Available

(E)-3-(2,4-Dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylic acid

Brivudine KSM — uracil acrylate

CAS No.: 57412-59-6
M. Formula: C7H6N2O4
MW: 182.13

Available

4-Glycidyloxycarbazole

Carvedilol KSM — glycidyl carbazole ether

CAS No.: 51997-51-4
M. Formula: C15H13NO2
MW: 239.27

Available

(R)-1-(Naphthalen-1-yl)ethanamine HCl

Cinacalcet HCl Chiral KSM

CAS No.: 82572-04-1
M. Formula: C12H14ClN
MW: 207.70

Available

3-(Trifluoromethyl)cinnamaldehyde

Cinacalcet HCl Intermediate — trifluoromethylcinnamaldehyde

CAS No.: 262268-58-6
M. Formula: C10H7F3O
MW: 200.16

Available

5-Cyanophthalide

Citalopram KSM — 5-cyanophthalide

CAS No.: 82104-74-3
M. Formula: C9H5NO2
MW: 159.14

Available

4-(Methylamino)-3-nitrobenzoic Acid

Dabigatran Intermediate — methylamino nitrobenzoic acid

CAS No.: 41263-74-5
M. Formula: C8H8N2O4
MW: 196.16

Available

4-Aminobenzonitrile

Dabigatran KSM — 4-aminobenzonitrile

CAS No.: 873-74-5
M. Formula: C7H6N2
MW: 118.14

Available

4-Chloro-3-nitrobenzoic Acid

Dabigatran KSM — 4-chloro-3-nitrobenzoic acid

CAS No.: 96-99-1
M. Formula: C7H4ClNO4
MW: 201.56

Available

Ethyl 3-(2-(((4-cyanophenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate

Dabigatran Etexilate Key Intermediate

CAS No.: 211915-84-3
M. Formula: C27H26N6O3
MW: 482.53

Available

Ethyl 3-(2-Pyridylamino)propionate

Dabigatran Intermediate — pyridylamino propionate ester

CAS No.: 103041-38-9
M. Formula: C10H14N2O2
MW: 194.23

Available

Ethyl 3-[[4-(Methylamino)-3-nitrobenzoyl]-pyridin-2-ylamino]propanoate

Dabigatran Advanced Intermediate

CAS No.: 429659-01-8
M. Formula: C18H20N4O5
MW: 372.38

Available

N-(4-Cyanophenyl)glycine

Dabigatran Intermediate — cyanophenylglycine

CAS No.: 42288-26-6
M. Formula: C9H8N2O2
MW: 176.17

Available

N-[3-Amino-4-(methylamino)benzoyl]-N-2-pyridinyl-β-alanine Ethyl Ester

Dabigatran Penultimate Intermediate

CAS No.: 212322-56-0
M. Formula: C18H22N4O3
MW: 342.39

Available

Methoxy Dapagliflozin

(2S,3R,4S,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol

CAS No.: 714269-57-5
M. Formula: C22H27ClO7
MW: 438.90

Available

1-(2,3-Dihydro-5-benzofuranyl)ethanone

Darifenacin HBr Intermediate

CAS No.: 90843-31-5
M. Formula: C10H10O2
MW: 162.19

Available

5-(2-Bromoethyl)-2,3-dihydrobenzofuran

Darifenacin HBr Intermediate

CAS No.: 127264-14-6
M. Formula: C10H11BrO
MW: 227.10

Available

(1-Methyl-4-piperidinyl)[3-[2-(3-chlorophenyl)ethyl]pyridinyl]methanone hydrochloride

Desloratadine Penultimate Intermediate

CAS No.: 119770-60-4
M. Formula: C20H24Cl2N2O
MW: 379.33

Available

2-Cyano-3-(3-chlorophenylethyl)pyridine

Desloratadine Intermediate

CAS No.: 31255-57-9
M. Formula: C14H11ClN2
MW: 242.71

Available

4-Amino-N-[2-(4-aminophenoxy)ethyl]-N-methylbenzeneethanamine

Dofetilide Diamino Intermediate

CAS No.: 115256-13-8
M. Formula: C17H23N3O
MW: 285.38

Available

Methyl-(4-nitrophenylethyl)-(4-nitrophenoxyethyl)amine

Dofetilide Dinitro Intermediate

CAS No.: 115287-37-1
M. Formula: C17H19N3O5
MW: 345.36

Available

1-(3-Chloropropyl)-1,3-dihydrobenzimidazol-2-one

Domperidone Intermediate

CAS No.: 62780-89-6
M. Formula: C10H11ClN2O
MW: 210.66

Available

5-Chloro-1-(4-piperidinyl)-2-benzimidazolidinone

Domperidone Intermediate

CAS No.: 53786-28-0
M. Formula: C12H14ClN3O
MW: 251.71

Available

(R)-1-(3-((1-methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)vinyl)-1H-indol-1-yl)ethanone

Eletriptan HBr Intermediate

CAS No.: 180637-88-1
M. Formula: C24H26N2O3S
MW: 422.40

Available

2-(Benzyloxy)-1-bromo-3-nitrobenzene

Eltrombopag Olamine KSM

CAS No.: 688363-79-3
M. Formula: C13H10BrNO3
MW: 308.13

Available

2'-(Benzyloxy)-3'-nitro-[1,1'-biphenyl]-3-carboxylic acid

Eltrombopag Olamine Intermediate

CAS No.: 1636137-55-7
M. Formula: C20H15NO5
MW: 349.34

Available

3'-Amino-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic Acid

Eltrombopag Olamine Penultimate Intermediate

CAS No.: 376592-93-7
M. Formula: C13H11NO3
MW: 229.23

Available

3-[5-(1,5-Dioxo-5-(p-fluorophenyl)pentyl]-4(S)-phenyl-2-oxazolidinone

Ezetimibe Intermediate

CAS No.: 189028-93-1
M. Formula: C20H18FNO4
MW: 355.36

Available

Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate

Febuxostat Penultimate Intermediate

CAS No.: 160844-75-7
M. Formula: C18H20N2O3S
MW: 344.43

Available

Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate

Febuxostat Intermediate

CAS No.: 161798-01-2
M. Formula: C14H13NO4S
MW: 291.32

Available

4-(4-Chloro-1-oxobutyl)-α,α-dimethylbenzeneacetic Acid Methyl Ester

Fexofenadine HCl KSM

CAS No.: 154477-54-0
M. Formula: C15H19ClO3
MW: 282.76

Available

3-Amino-3-azabicyclo[3,3,0]octane Hydrochloride

Gliclazide KSM

CAS No.: 58108-05-7
M. Formula: C7H15ClN2
MW: 162.66

Available

4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride

Imatinib Mesylate Intermediate

CAS No.: 106261-49-8
M. Formula: C13H20Cl2N2O2
MW: 307.22

Available

N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine

Imatinib Mesylate Intermediate

CAS No.: 152460-10-1
M. Formula: C16H15N5
MW: 277.32

Available

3-Bromo-5-(bromoacetyl)salicylamide

Labetalol Intermediate

CAS No.: 2924103-17-1
M. Formula: C9H7Br2NO3
MW: 336.97

Available

5-(2-Bromoacetyl)-2-hydroxybenzamide

Labetalol Intermediate

CAS No.: 73866-23-6
M. Formula: C9H8BrNO3
MW: 258.07

Available

5-(2,2-Dibromoacetyl)-2-hydroxybenzamide

Labetalol Intermediate

CAS No.: NA
M. Formula: C9H7Br2NO3
MW: 337.0

Available

5-Acetyl salicylamide

Labetalol Intermediate — 5-acetyl salicylamide

CAS No.: 40187-51-7
M. Formula: C9H9NO3
MW: 179.2

Available

5-Acetyl-3-bromo-2-hydroxybenzamide

Labetalol Intermediate

CAS No.: NA
M. Formula: C9H8BrNO3
MW: 258.07

Available

4-((1H-1,2,4-Triazol-1-yl)methyl)benzonitrile

Letrozole Intermediate

CAS No.: 112809-25-3
M. Formula: C10H8N4
MW: 184.2

Available

4-(4-Cyanobenzyl)-1,2,4-triazole

Letrozole Impurity

CAS No.: 112809-27-5
M. Formula: C10H8N4
MW: 184.2

Available

4-[(4-Cyanophenyl)-(1H-1,2,4-triazol-1-yl)methyl]benzamide

Letrozole MonoAmide Impurity

CAS No.: 2500927-47-7
M. Formula: C17H13N5O
MW: 303.33

Available

4,4'-((1H-1,2,4-Triazol-1-yl)methylene)dibenzamide

Letrozole Diamide Impurity

CAS No.: 2170106-13-3
M. Formula: C17H15N5O2
MW: 321.34

Available

4,4'-(4H-1,3,4-Triazol-4-ylmethylene)dibenzonitrile

Letrozole Impurity A

CAS No.: 112809-52-6
M. Formula: C17H11N5
MW: 285.30

Available

4,4',4''-Methanetriyltribenzonitrile

Letrozole Impurity B

CAS No.: 113402-31-6
M. Formula: C22H13N3
MW: 319.36

Available

N-Acetyl-3,5-diiodotyrosine ethyl ester

Levothyroxine Sodium KSM — diiodotyrosine ester

CAS No.: 21959-36-4
M. Formula: C13H15I2NO4
MW: 503.07

Available

(1R)-2-Chloro-1-(2,4-dichlorophenyl)ethan-1-ol

Luliconazole Chiral Intermediate (R-isomer)

CAS No.: 114446-57-0
M. Formula: C8H7Cl3O
MW: 225.50

Available

(1S)-2-Chloro-1-(2,4-dichlorophenyl)ethan-1-ol

Luliconazole Chiral Intermediate (S-isomer)

CAS No.: 126534-31-4
M. Formula: C8H7Cl3O
MW: 225.50

Available

(S)-2-Chloro-1-(2,4-dichlorophenyl)ethyl methanesulfonate

Luliconazole Mesylate Intermediate

CAS No.: 229334-55-8
M. Formula: C9H9Cl3O3S
MW: 303.59

Available

1-(3-Carboxypyrid-2-yl)-2-phenyl-4-methylpiperazine

Mirtazapine Intermediate

CAS No.: 61338-13-4
M. Formula: C17H19N3O2
MW: 297.36

Available

2-(4-Methyl-2-phenyl-1-piperazinyl)-3-pyridinemethanol

Mirtazapine Intermediate

CAS No.: 61337-89-1
M. Formula: C17H21N3O
MW: 283.37

Available

(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide

Palonosetron HCl Chiral KSM

CAS No.: 135729-78-1
M. Formula: C18H24N2O
MW: 284.40

Available

Palonosetron-3-ene Hydrochloride

Palonosetron HCl Intermediate

CAS No.: 135729-55-4
M. Formula: C19H23ClN2O
MW: 330.85

Available

2-((1-Phenoxypropan-2-yl)amino)ethanol

Phenoxybenzamine HCl Intermediate

CAS No.: 381725-50-4
M. Formula: C11H17NO2
MW: 195.26

Available

tert-Butyl (3R,5S,E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoate

Pitavastatin Calcium Penultimate Intermediate

CAS No.: 586966-54-3
M. Formula: C29H32FNO4
MW: 477.57

Available

tert-Butyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate

Pitavastatin Calcium Intermediate

CAS No.: 147489-06-3
M. Formula: C32H36FNO4
MW: 517.63

Available

6-Methoxy-2-(4-methoxyphenyl)-1-benzothiophene

Raloxifene HCl KSM — dimethoxybenzothiophene

CAS No.: 63675-74-1
M. Formula: C16H14O2S
MW: 270.35

Available

2-(2-Aminopropan-2-yl)-N-[(4-fluorophenyl)methyl]-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide

Raltegravir Potassium Intermediate

CAS No.: 518048-03-8
M. Formula: C16H19FN4O3
MW: 334.35

Available

1-(2-Methoxyphenoxy)-2,3-epoxypropane

Ranolazine KSM — epoxy propane ether

CAS No.: 2210-74-4
M. Formula: C10H12O3
MW: 180.20

Available

N-(2,6-Dimethylphenyl)-2-(piperazin-1-yl)acetamide

Ranolazine Intermediate — piperazine acetamide

CAS No.: 5294-61-1
M. Formula: C14H21N3O
MW: 247.34

Available

1-(2-(Methylamino)ethyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate

Revefenacin Penultimate Intermediate

CAS No.: 743460-48-2
M. Formula: C21H27N3O2
MW: 353.47

Available

4-Piperidyl N-(2-biphenyl)carbamate

Revefenacin KSM — piperidine biphenyl carbamate

CAS No.: 171722-92-2
M. Formula: C18H20N2O2
MW: 296.37

Available

4-(3,4-Dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenone (Tetralone)

Sertraline HCl KSM — Tetralone

CAS No.: 79560-19-3
M. Formula: C16H12Cl2O
MW: 291.17

Available

4-(3,4-Dichlorophenyl)-N-methyl-3,4-dihydro-2H-naphthalen-1-imine (Schiff-Base)

Sertraline HCl Schiff-Base Intermediate

CAS No.: 79560-20-6
M. Formula: C17H15Cl2N
MW: 304.21

Available

(R)-3-(7-Cyano-5-(2-((2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl)amino)propyl)indolin-1-yl)propyl benzoate oxalate

Silodosin Penultimate Intermediate

CAS No.: 885340-12-5
M. Formula: C33H36F3N3O7
MW: 671.66

Available

(R)-(-)-3-Quinuclidinol

Solifenacin Succinate Chiral KSM

CAS No.: 25333-42-0
M. Formula: C7H13NO
MW: 127.18

Available

(S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline

Solifenacin Succinate Chiral Intermediate (S-isomer)

CAS No.: 118864-75-8
M. Formula: C15H15N
MW: 209.29

Available

1-Phenyl-1,2,3,4-tetrahydroisoquinoline

Solifenacin Succinate Intermediate (racemic)

CAS No.: 22990-19-8
M. Formula: C15H15N
MW: 209.29

Available

1,2-Dihydro-1-phenylisoquinoline

Solifenacin Succinate Intermediate

CAS No.: 134021-15-1
M. Formula: C15H13N
MW: 207.27

Available

Ethyl 1-(Ethoxy-2-oxoethyl)piperidine-4-carboxylate

Solifenacin Succinate Intermediate

CAS No.: 1838-39-7
M. Formula: C12H21NO4
MW: 243.30

Available

Ethyl Isonipecotate

Solifenacin Succinate KSM — ethyl isonipecotate

CAS No.: 1126-09-6
M. Formula: C8H15NO2
MW: 157.21

Available

N-Phenethylbenzamide

Solifenacin Succinate Intermediate

CAS No.: 3278-14-6
M. Formula: C15H15NO
MW: 225.29

Available

5-Fluorooxindole

Sunitinib Malate KSM — 5-fluorooxindole

CAS No.: 56341-41-4
M. Formula: C8H6FNO
MW: 151.14

Available

5-Formyl-2,4-dimethyl-3-pyrrolecarboxylic Acid

Sunitinib Malate KSM

CAS No.: 253870-02-9
M. Formula: C8H9NO3
MW: 167.16

Available

3,4-Dihydro-2H-pyrrol-5-amine hydrochloride

Tipiracil HCl KSM — iminopyrrolidine HCl

CAS No.: 7544-75-4
M. Formula: C4H9ClN2
MW: 120.58

Available

5-Chloro-6-(chloromethyl)pyrimidine-2,4(1H,3H)-dione

Tipiracil HCl Intermediate

CAS No.: 73742-45-7
M. Formula: C5H4Cl2N2O2
MW: 195.00

Available

6-(Chloromethyl)pyrimidine-2,4(1H,3H)-dione

Tipiracil HCl Intermediate

CAS No.: 18592-13-7
M. Formula: C5H5ClN2O2
MW: 160.56

Available

(1R,4r)-4-(((1r,4R)-4-(aminomethyl)cyclohexanecarboxamido)methyl)cyclohexanecarboxylic acid

Tranexamic acid Impurity-E

CAS No.: 82755-59-7
M. Formula: C16H28N2O3
MW: 296.41

Available

(RS)-4-(Aminomethyl)cyclohex-1-enecarboxylic acid

Tranexamic acid Impurity-C

CAS No.: 330838-52-3
M. Formula: C8H13NO2
MW: 155.19

Available

(trans,trans)-4,4'-(Azanediylbis(methylene))dicyclohexanecarboxylic acid

Tranexamic acid Impurity-A

CAS No.: 93940-19-3
M. Formula: C16H27NO4
MW: 297.39

Available

cis-4-(Aminomethyl)cyclohexanecarboxylic acid

Tranexamic acid Impurity-B

CAS No.: 1197-17-7
M. Formula: C8H15NO2
MW: 157.21

Available

trans-Methyl 4-(aminomethyl)cyclohexanecarboxylate

Tranexamic acid Impurity

CAS No.: 50738-63-1
M. Formula: C9H17NO2
MW: 171.24

Available

(3S,5S,6R)-3-Amino-6-methyl-5-phenyl-1-(2,2,2-trifluoroethyl)piperidin-2-one hydrochloride

Ubrogepant Penultimate Intermediate

CAS No.: 1375470-88-4
M. Formula: C14H18ClF3N2O
MW: 322.75

Available

tert-Butyl ((3S,5S,6R)-6-methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)piperidin-3-yl)carbamate

Ubrogepant Intermediate

CAS No.: 1456803-35-2
M. Formula: C19H25F3N2O3
MW: 386.42

Available

(S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile

Vildagliptin KSM

CAS No.: 207557-35-5
M. Formula: C7H9ClN2O
MW: 172.61

Available

3-Aminoadamantan-1-ol

Vildagliptin KSM — adamantanol

CAS No.: 702-82-9
M. Formula: C10H17NO
MW: 167.25

Available

(2R,3S)-rel-3-(6-Chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

Voriconazole Penultimate Intermediate

CAS No.: 137234-75-4
M. Formula: C16H13ClF3N5O
MW: 383.76

Available

4-(1-Bromoethyl)-6-chloro-5-fluoropyrimidine

Voriconazole KSM

CAS No.: 188416-28-6
M. Formula: C6H5BrClFN2
MW: 239.47